Orr Biologicals / Neuroscience

One neuron is a start.
Not the whole brain.

NeuroML is a provenance-first connectomics environment. Its first working record is one proofread MICrONS mouse V1 neuron, with the dataset's own skeleton and every detected synaptic partner. The fruit-fly connectome is a separate integration, not a number we borrow for a screenshot.

Open NeuroML Developer contract
Two-dimensional projection of the measured MICrONS skeleton of root 864691135479404742, a proofread L5NP neuron in mouse V1, with incoming and outgoing synapses. L5NP / V1 / 2D projection
Measured morphology and detected synapses from the MICrONS record. The colours separate axon, dendrite, incoming synapses and outgoing synapses; this is not microscopy or a synthetic cell.

Record / MICrONS minnie65

A cell you can trace back.

Root 864691135479404742 is read at pinned materialization 1926. The record carries its proofreading status, skeleton hash and partner root identifiers so a researcher can compare it with the source.

Skeleton nodes
4,738
Detected synapses
2,056
Dataset version
1926

1,171 outgoing · 885 incoming. Automated synapse detection is not a complete manual reconstruction. This is one neuron from a cubic-millimetre volume, not a whole-brain connectome.

Inspect the source record

01 / Two environments

Shared method.
Different evidence.

Mouse and fly data do not describe the same animal, preparation or release. They share an interface and an evidence vocabulary; they do not share counts.

01 / MouseLive record

Mouse brain

The first vertical slice connects one proofread L5NP neuron in V1 to its measured skeleton and synaptic partners from MICrONS. The source table, materialization and limitations are visible on the record page.

  • Record1 verified neuron
  • Connectivity2,056 detected synapses
  • Coverage1 of 5 registered datasets
Open the mouse environment
02 / Fruit flyIntegration pending

Fruit fly

A published fruit-fly connectome exists, but it is not merged into this site and no fly totals are quoted here. Integration begins with a release audit: dataset version, annotation status, identifier policy and licence.

  • StatusSeparate implementation
  • CountsNot verified here
  • Next gateRelease audit
Read the integration boundary

02 / Evidence boundary

The distinction is
the interface.

A predicted edge is not a measured synapse.
Verified observation

The MICrONS skeleton, its proofreading status and every synapse returned by synapses_pni_2 at version 1926.

Dataset annotation

The L5NP cell-type label comes from a dataset classifier. The page names it as an annotation rather than upgrading it to manual ground truth.

Not present

No mouse activity prediction, no fly graph and no validated model experiment is shown as live. DATA UNAVAILABLE is a valid result; an estimate presented as biology is not.

03 / What comes next

Build coverage.
Keep the limits.

The next mouse milestone is a small set of proofread neurons at one pinned version, followed by a real connectivity graph. The next fly milestone is an audit of the existing viewer against a specific published release. The public API remains a contract, not a live endpoint.

Research approach Read the evidence rules